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research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain

50 citations, May 2019 in “Drugs”

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications

5 citations, December 2022 in “Toxins”

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses

13 citations, October 2010 in “Pharmacogenomics”

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

140 citations, February 2014 in “Neuron”

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

research State-Dependent Signaling by Cav1.2 Regulates Hair Follicle Stem Cell Function

27 citations, June 2013 in “Genes & development”

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

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Community Join

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community Ligand Chem cease trading Pyrilutamide

in Product 14 upvotes 2 years ago

Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

community Dropping RU , not responding..

in Treatment 6 upvotes 1 year ago

The user has been using RU58841 for 6 months without noticeable results and is considering dropping it while continuing oral minoxidil, daily dutasteride, and topical minoxidil. Another user suggests visiting a dermatologist to check for other conditions.

community You will lose hair if your prostaglandins aren't in balance

in Research/Science 55 upvotes 2 months ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community Blaming Finasteride doesn't help you solve anything: dry eyes

in Finasteride/Dutasteride 50 upvotes 3 months ago

Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 6 months ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

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