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Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

research Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

38 citations , June 2005 in “Matrix Biology”

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

research Identification of MicroRNAs Involved in Growth Arrest and Cell Death in Hydrogen Peroxide-Treated Human Dermal Papilla Cells

12 citations , April 2014 in “Molecular Medicine Reports”

Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.

research Minoxidil Cannot Be Used To Target Lysyl Hydroxylases During Postnatal Mouse Lung Development: A Cautionary Note

2 citations , October 2020 in “Journal of Pharmacology and Experimental Therapeutics”

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

research A Window into Mammalian Basement Membrane Development: Insights from the mTurq2-Col4a1 Mouse Model

September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.

research Comprehensive Transcriptome and Methylome Analysis Delineates the Biological Basis of Hair Follicle Development and Wool-Related Traits in Merino Sheep

112 citations , September 2021 in “BMC Biology”

Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.

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community Dutasteride experience and blood work results 1 1/2 years later

in Finasteride/Dutasteride 1 upvotes 4 months ago

The user shared their experience with dutasteride for hair loss prevention, noting side effects like muscle weakness and brain fog, and observed increased testosterone levels. They recommend starting with a low dose and adjusting based on individual needs and blood work results.

community A lot of blood tests that I have done until now (Mainly Hormones).

in Finasteride/Dutasteride 5 upvotes 4 years ago

The user shared their experience with hair loss treatments, including oral and topical Finasteride and Minoxidil, and detailed various blood test results to track hormonal changes. They noted that while DHT levels initially decreased with topical Finasteride, they later increased, but they observed positive results in hair growth.

community Finasteride doubled my testosterone & estrogen

in Chat 265 upvotes 1 month ago

Finasteride increased testosterone and estrogen, stopped hair loss, and promoted regrowth. Users discussed side effects like libido changes and considered adding minoxidil and aromatase inhibitors.