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This study found that cutaneous squamous cell carcinomas in mice infected with murine papillomavirus preferentially arise from Lgr5+ progenitor cells, while squamous cell dysplasia does not.

This study found that the phenotype of Hedgehog/Gli-driven skin tumors in mice depends on the cell of origin, tissue context, and level of oncogenic signaling.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

This review discusses stem cell behavior, highlighting their plasticity in tissue repair and the impact of somatic mutations on clonal expansion in early cancer, but reports no new experimental results.

This review discusses environmental reprogramming and the plasticity of epithelial cells, emphasizing their potential for new cell therapy approaches; it reports no new experimental results.