research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
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5 / 655 results research Hyperandrogenism Due to a Testosterone-Secreting Sertoli-Leydig Cell Tumor Associated With a Dehydroepiandrosterone Sulfate-Secreting Adrenal Adenoma in a Postmenopausal Woman: Case Presentation and Review of Literature
research Finasteride-related Leydig cell tumour: report of a case and literature review
Finasteride use may be linked to rare testicular tumor, but more research needed.
research Testosterone-Secreting Adrenal Adenoma That Contained Crystalloids of Reinke in an Adult Female Patient
This case study describes a testosterone-secreting adrenal adenoma in a 55-year-old woman, highlighting the presence of Reinke's crystalloids, suggesting that Leydig cells may play a role in such tumors.
research Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review
This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.
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