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GlossaryLeuprolide (Leuprorelin)

medication that reduces hormone levels to treat certain conditions

Leuprolide, also known as Lupron, is a medication that acts as a gonadotropin-releasing hormone (GnRH) agonist. It is commonly used to treat hormone-sensitive conditions such as prostate cancer, endometriosis, and uterine fibroids by reducing the production of certain hormones like testosterone and estrogen. This reduction can help manage symptoms and slow the progression of these conditions.

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research Gonadotropin-Releasing Hormone Agonist Treatment in Postmenopausal Women with Hyperandrogenism of Ovarian Origin

36 citations, May 2011 in “The Journal of Clinical Endocrinology & Metabolism”

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Presentation of a Meningioma in a Transwoman After Nine Years of Cyproterone Acetate and Estradiol Intake: Case Report and Literature Review

research Presentation of a Meningioma in a Transwoman After Nine Years of Cyproterone Acetate and Estradiol Intake: Case Report and Literature Review

34 citations, November 2017 in “Gynecological Endocrinology”

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

research Hypothalamic Hamartoma with Precocious Puberty and Gelastic Seizures in a Boy: Case Report

October 2013 in “International Journal of Pediatric Endocrinology/International journal of pediatric endocrinology”

A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.

research Clinical Case Seminar: Postmenopausal Androgen Excess - Challenges in Diagnostic Work-Up and Management of Ovarian Thecosis

20 citations, October 2017 in “Clinical Endocrinology”

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Androgenic Effects on Ventricular Repolarization: A Translational Study from Pharmacovigilance Databases to iPSC-Cardiomyocytes

research Androgenic Effects on Ventricular Repolarization: A Translational Study from Pharmacovigilance Databases to iPSC-Cardiomyocytes

October 2019 in “European heart journal”

Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.

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community 21 months on topical minoxidil and full HRT

in Transgender 214 upvotes 6 months ago

The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 122 upvotes 11 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.