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    Did you mean Late-onset Congenital Adrenal Hyperplasia?
    GlossaryNon-Classical Adrenal Hyperplasia (Late-onset Congenital Adrenal Hyperplasia)

    partial enzyme deficiency causing excess androgen production

    Non-Classical Adrenal Hyperplasia (NCAH) is a milder form of congenital adrenal hyperplasia that typically presents later in life, often during adolescence or adulthood. It is caused by a partial deficiency in the enzyme 21-hydroxylase, leading to an overproduction of androgens (male hormones). Symptoms can include irregular menstrual cycles, excessive hair growth (hirsutism), and acne in females, while males may experience early signs of puberty.

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      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      An Update on Congenital Adrenal Hyperplasia

      research An Update on Congenital Adrenal Hyperplasia

      151 citations, December 2004 in “Annals of the New York Academy of Sciences”
      Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
      Hirsutism in Young Girls: Beyond PCOS

      research Hirsutism in Young Girls: Beyond PCOS

      October 2024 in “Journal of the Endocrine Society”
      Hirsutism in young girls can have causes other than PCOS, so diagnoses should be reassessed if treatments don't work.
      Menstrual Irregularity in Hirsute Women

      research Menstrual Irregularity in Hirsute Women

      September 1997 in “Journal of the European Academy of Dermatology and Venereology”
      Hirsute women with ovarian-sourced hirsutism are more likely to have irregular periods, with higher BMI and altered hormone ratios.

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      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 9 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community "DHT Itch" and onset Seborrheic Dermatitis

      in Research/Science  76 upvotes 1 year ago
      The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.