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In this study, it was observed that NIPAL4 mutations linked to autosomal recessive congenital ichthyosis lead to abnormal skin barrier function due to cytotoxic effects disrupting lipid structure and organization, which topical treatments only partially ameliorated.

This study found that African and Caucasian hair contain the most lipids, and depletion of these lipids leads to less water retention and increased water desorption, with Caucasian hair showing improved breaking tenacity after lipid extraction.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.

This research reported that a newly developed dually crosslinked gelatin-alginate-based hydrogel scaffold enhances mechanical strength, promotes corneal tissue regeneration, and reduces scarring in rabbit models, suggesting potential applications in corneal tissue engineering.