research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
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research Alopecia Areata Patients Show Deficiency of FOXP3+CD39+ T Regulatory Cells and Clonotypic Restriction of Treg TCRβ-Chain, Highlighting the Immunopathological Aspect of the Disease
Patients with Alopecia areata have fewer specific immune cells that normally regulate the immune system, which may contribute to the condition.
research The Potential of Regulatory T Cell-Based Therapies for Alopecia Areata
Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
research Biological Therapy in the Treatment of Melanoma
Biological therapy boosts the immune system to effectively fight melanoma.
research Induction of T Cell Exhaustion by JAK1/3 Inhibition in the Treatment of Alopecia Areata
Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
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5 / 18 resultscommunity Question about when to start Finastride? i am on Minoxidil (23M)
by
mmmkkk
in Finasteride
129 upvotes
1 month ago A 23-year-old plans to use Minoxidil for 4 months, then add Finasteride to assess their effectiveness for hair loss. They will track progress with photos and consider switching treatments if results are unsatisfactory.
community Acute shedding episodes. Had telogen effluvium last year. Remission for a few months(thought I was over the shedding stuff 🥲). Now if I have any major stress days, THAT day I get a major shed and a few days after.
The user experiences immediate hair shedding linked to stress, unlike typical telogen effluvium, and is seeking answers. A suggestion was made to use spironolactone and topical minoxidil to address potential DHT-related shedding.
community 8 month progress, slowly but surely. Topical Min/Fin, Microneedle, Niz, etc....
A user reports hair regrowth after 8 months using treatments including topical Minoxidil/Finasteride, microneedling, Nizoral shampoo, Pyrilutamide, GHK-Cu/Min topical, and supplements like fish collagen peptides, zinc, and vitamin D3. They've seen progress but slower regrowth in the midsection of the scalp and are seeking advice to improve it.
community Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)
A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.
community September 2023 vs December 2024
The user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil due to side effects but is experiencing further hair recession. They plan to double the dosage, despite mixed feedback on the effectiveness and potential side effects of the treatments.