82 citations
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March 2016 in “Autoimmunity reviews”
This review explores animal models of alopecia areata, particularly focusing on the insights they've provided into the disease's immune mechanisms and potential treatment approaches, without reporting new experimental data.
27 citations
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April 2018 in “Journal of autoimmunity”
In this study, iNKT10 cells were found to play a significant role in preventing and treating alopecia areata in a humanized mouse model, suggesting these cells could have potential in managing related autoimmune disorders.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study provides evidence that innate lymphoid cells-type 1 can induce alopecia areata in human hair follicles, challenging the view that it is solely a CD8+ Tcell-driven autoimmune disease.