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GlossaryKLF4 (Kruppel-like factor 4)

transcription factor regulating cell growth and differentiation

KLF4, or Kruppel-like factor 4, is a protein that plays a crucial role in regulating cell growth, differentiation, and maintaining stem cell pluripotency. It is involved in various biological processes, including skin and hair follicle development, and has been studied for its potential implications in cancer and regenerative medicine.

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Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis

research Extracellular Vesicles From 3D Cultured Dermal Papilla Cells Improve Wound Healing Via Krüppel-Like Factor 4/Vascular Endothelial Growth Factor A-Driven Angiogenesis

1 citations , January 2023 in “Burns and trauma”

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing

research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing

23 citations , June 2012 in “PLOS ONE”

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Function of KLF4 in Stem Cell Biology

research Function of KLF4 in Stem Cell Biology

5 citations , August 2013 in “InTech eBooks”

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Wnt Signaling: The Good and the Bad

research Wnt Signaling: The Good and the Bad

48 citations , July 2008 in “Acta Biochimica et Biophysica Sinica”

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Development and Homeostasis of the Skin Epidermis

research Development and Homeostasis of the Skin Epidermis

85 citations , July 2012 in “Cold Spring Harbor perspectives in biology”

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

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