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GlossaryKLF4 (Kruppel-like factor 4)

transcription factor regulating cell growth and differentiation

KLF4, or Kruppel-like factor 4, is a protein that plays a crucial role in regulating cell growth, differentiation, and maintaining stem cell pluripotency. It is involved in various biological processes, including skin and hair follicle development, and has been studied for its potential implications in cancer and regenerative medicine.

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Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species

research Ultraviolet B Preconditioning Enhances the Hair Growth-Promoting Effects of Adipose-Derived Stem Cells Via Generation of Reactive Oxygen Species

41 citations, July 2012 in “Stem Cells and Development”

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

research MicroRNA Control of Signal Transduction

1066 citations, March 2010 in “Nature Reviews Molecular Cell Biology”

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

research Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia

6 citations, April 2012 in “PloS one”

The local environment is crucial for cell development in the tongue.

research Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells

July 2023 in “Molecules”

Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.

research Wnt/β-Catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration

94 citations, June 2016 in “The FASEB Journal”

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

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