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GlossaryKeratin-Associated Proteins (KRTAP)

bind to keratin fibers, strengthening hair and nails

Keratin-Associated Proteins (KAPs) are a group of proteins that bind to keratin fibers, which are the structural components of hair, nails, and the outer layer of skin. They play a crucial role in the formation and strength of these keratin structures by cross-linking with keratin, thereby enhancing the rigidity and resilience of hair and other keratinized tissues.

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research Mammalian Keratin-Associated Proteins (KRTAPs) Subgenomes: Disentangling Hair Diversity and Adaptation to Terrestrial and Aquatic Environments

65 citations , September 2014 in “BMC genomics”

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

research Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-option in the Evolution of the Hair Follicle

November 2022 in “Research Square (Research Square)”

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

research Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-Option in the Evolution of the Hair Follicle

2 citations , March 2023 in “BMC ecology and evolution”

Some hair protein genes evolved early and were adapted for use in hair follicles.

research The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes

10 citations , November 2021 in “International journal of molecular sciences”

Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.

Cornified Epithelial Teeth of Jawless Vertebrates Contain Proteins Similar to Keratin-Associated Proteins of Mammalian Skin Appendages

research Cornified Epithelial Teeth of Jawless Vertebrates Contain Proteins Similar to Keratin-Associated Proteins of Mammalian Skin Appendages

May 2025 in “Journal of Developmental Biology”

Jawless vertebrates have teeth proteins similar to those in mammalian hair and nails.

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