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GlossaryKeratin-Associated Proteins (KRTAP)

bind to keratin fibers, strengthening hair and nails

Keratin-Associated Proteins (KAPs) are a group of proteins that bind to keratin fibers, which are the structural components of hair, nails, and the outer layer of skin. They play a crucial role in the formation and strength of these keratin structures by cross-linking with keratin, thereby enhancing the rigidity and resilience of hair and other keratinized tissues.

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research Mammalian Keratin-Associated Proteins (KRTAPs) Subgenomes: Disentangling Hair Diversity and Adaptation to Terrestrial and Aquatic Environments

65 citations , September 2014 in “BMC genomics”

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

research Krtap16: Characterization of a New Hair Keratin-Associated Protein Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13

47 citations , September 2004 in “Journal of Biological Chemistry”

Hoxc13 regulates specific hair protein genes on mouse chromosome 16.

research Identification of Ovine KRTAP28-1 and Its Association with Wool Fiber Diameter

25 citations , April 2019 in “Animals”

KRTAP28-1 gene can help breed sheep with finer wool.

Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-Option in the Evolution of the Hair Follicle

research Ancient Lineages of the Keratin-Associated Protein (KRTAP) Genes and Their Co-Option in the Evolution of the Hair Follicle

2 citations , March 2023 in “BMC ecology and evolution”

Some hair protein genes evolved early and were adapted for use in hair follicles.

research Application of PCR Technique to Detect Polymorphism of the KRTAP1.1 Gene in Three Sheep Breeds: A Review

1 citations , April 2021 in “IntechOpen eBooks”

The PCR technique can identify genetic differences in a wool-related gene among different sheep breeds, which may help improve wool and pelt quality.

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