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GlossaryKeratin 19 (KRT19)

protein in epithelial cells used as a cancer biomarker

Keratin 19 (KRT19 or CK19) is a type of protein found in the epithelial cells that line the surfaces and cavities of organs. It plays a crucial role in maintaining the structural integrity of these cells. In medical diagnostics, KRT19 is often used as a biomarker to detect certain types of cancers, as its expression levels can be indicative of tumor presence and progression.

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research Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin

62 citations, November 2009 in “Aging Cell”

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells

10 citations, August 2020 in “Current protocols in stem cell biology”

Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.

research Proteomics Analysis of the Secondary Hair Follicle Cycle in Liaoning Cashmere Goat

5 citations, May 2021 in “Small ruminant research”

The study found specific proteins that could mark different growth stages of cashmere goat hair and may help improve cashmere production.

research Noncoding dsRNA Stimulates Exosome Biosynthesis to Regulate Skin Regeneration

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Noncoding dsRNA helps produce exosomes that aid in skin regeneration.

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

54 citations, January 2016 in “Cell reports”

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

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