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GlossaryKeratin 17 (KRT17)

protein crucial for skin, hair, and nail structure

Keratin 17 (K17) is a type of protein found in the skin, hair follicles, and nails, playing a crucial role in their structural integrity and resilience. It is also involved in cellular processes like growth and repair, and its abnormal expression is linked to certain skin disorders and cancers.

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research Comparative Anatomy of Mouse and Human Nail Units

55 citations , February 2013 in “The Anatomical Record”

Mouse nails are similar to human nails, making them useful for studying nail diseases.

research Promoter Methylation Changes in KRT17: A Novel Epigenetic Marker for Wool Production in Angora Rabbit

2 citations , May 2022 in “International journal of molecular sciences”

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

research A Case of Steatocystoma Multiplex in a Psoriatic Patient During Treatment with Anti-IL-12/23

2 citations , January 2020 in “Skin Appendage Disorders”

Ustekinumab treatment may reveal a genetic tendency for steatocystoma multiplex in psoriasis patients.

Unlocking the Genetic Secrets of Dorper Sheep: Insights Into Wool Shedding and Hair Follicle Development

research Unlocking the Genetic Secrets of Dorper Sheep: Insights Into Wool Shedding and Hair Follicle Development

December 2024 in “Frontiers in Veterinary Science”

Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.

research Homozygous Dominant Missense Mutation in Keratin 17 Leads to Alopecia in Addition to Severe Pachyonychia Congenita

22 citations , February 2012 in “Journal of Investigative Dermatology”

A specific gene mutation causes severe skin and nail issues and hair loss.

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