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GlossaryKeratin 15 (KRT15)

protein crucial for hair follicle stem cell regulation

Keratin 15 (K15) is a type of protein found in the hair follicles and skin, playing a crucial role in the structural integrity and function of these tissues. It is particularly important for the maintenance and regeneration of hair, as it is involved in the regulation of stem cells within the hair follicle, which are essential for hair growth and repair.

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AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis

research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis

December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells

10 citations, August 2020 in “Current protocols in stem cell biology”

Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.

Noncoding dsRNA Stimulates Exosome Biosynthesis to Regulate Skin Regeneration

research Noncoding dsRNA Stimulates Exosome Biosynthesis to Regulate Skin Regeneration

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Noncoding dsRNA helps produce exosomes that aid in skin regeneration.

Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin

research Hedgehog Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and Aged Human Skin

62 citations, November 2009 in “Aging Cell”

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

research Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating

33 citations, May 2018 in “Stem Cell Reports”

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

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