research A Mouse Kindling Model of Perimenstrual Catamenial Epilepsy
Neurosteroids help reduce seizures, but their withdrawal increases seizure activity.
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research Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
research Novel Anticonvulsive Effects of Progesterone in a Mouse Model of Hippocampal Electrical Kindling
Progesterone can reduce seizures without relying on the GABAA receptor pathway.
research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6-Hz and Kindling Models of Epilepsy
Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.
research Faculty Opinions Recommendation of Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis
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