November 2022 in “Journal of Investigative Dermatology” This study found that DermaCult™ Keratinocyte Expansion Medium allows for significantly extended growth of human epidermal keratinocytes while maintaining their differentiation potential.
January 2008 in “Anhui nongye kexue” In this study, researchers established a model using Mongolia Sheep hair follicles to investigate growth mechanisms, noting that adding insulin and hydrocortisone helped maintain follicle shape during extended culture.
June 2021 in “Experimental and Therapeutic Medicine” In this study, mouse hair follicle stem cells cultured in mouse embryonic fibroblast/keratinocyte serum-free medium exhibited the highest proliferative ability and stronger osteogenic differentiation potential, similar to hair follicle dermal papilla cells.
August 1994 in “Toxicology in Vitro” This study standardized a reproducible three-dimensional human skin model for testing skin tumor promoters, using methods that do not require human skin sourcing.
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January 1997 in “Pharmacology & toxicology” This study found that human keratinocytes' sensitivity and response to vitamin D3 analogues vary based on cell density, serum availability, and calcium concentration.