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research Cryo-Electron Microscopy of Trichocyte (Hard α-Keratin) Intermediate Filaments Reveals a Low-Density Core

48 citations , January 2002 in “Journal of Structural Biology”

This study reports that trichocyte intermediate filaments from rat vibrissae and human hair follicles may contain a hollow region at their core, suggesting unique structural properties.

research Understanding the Nano‐topography Changes and Cellular Influences Resulting from the Surface Adsorption of Human Hair Keratins

41 citations , May 2012 in “Advanced Healthcare Materials”

This study found that human hair keratin coatings enhanced adhesion and proliferation of L929 mouse fibroblasts compared to uncoated and collagen type 1 surfaces, suggesting keratin's potential as a surface coating for cell cultures.

research A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

192 citations , April 2019 in “ACS nano”

In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.

research Organization of microfibrils in keratin fibers studied by X-ray scattering

63 citations , December 1998 in “Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology”

The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.

research Autosomal Recessive Hypotrichosis with Woolly Hair Caused by a Mutation in the Keratin 25 Gene Expressed in Hair Follicles

50 citations , February 2016 in “Journal of Investigative Dermatology”

A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.

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Community Join

5 / 145 results

community a new supplement just released

12 upvotes 8 years ago

A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

community Affordable shampoo and conditioner suggestions for long but thinning hair?

2 upvotes 11 months ago

A user with thinning, curly, dry hair is seeking affordable shampoo and conditioner recommendations. They are using oral minoxidil and apply argan oil, but dislike products with keratin and biotin, and another user suggests ketoconazole shampoo for added density and DHT blocking.

community Let's talk keratin products and hair loss

2 upvotes 11 months ago

OP is considering using a keratin gel to improve hair quality and is concerned about its safety and visual impact on a slightly balding crown. Users discuss shampoo frequency, with some suggesting less frequent use for better hair health, but OP prefers regular shampoo and conditioner for silky hair.

community Diffuse thinner - How to cosmetically increase the thickness of your hair strands themselves when you don't have bald spots?

6 upvotes 1 year ago

To increase hair density appearance, options include using hair fibers, volume powders, scalp micropigmentation, and a combination of sea salt and holding sprays. Tape-in extensions and clip-in fringes are also considered, but cost and maintenance are concerns.

community Thoughts on this topical? Has a combination going on but are they really heavy hitters

4 upvotes 7 months ago

Follicium XR™ is a topical treatment for hair loss containing RU58841, AHK-Cu, GHK-Cu Peptide, caffeine, D-Biotin, methylene blue, keratin, and spermidine. RU58841 is considered the most effective ingredient, but concerns exist about its stability in water.

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