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    GlossaryPotassium Channel Openers (KCOs)

    drugs that activate potassium channels, aiding in cell stabilization

    Potassium Channel Openers (KCOs) are a class of drugs that activate potassium channels in cell membranes, allowing potassium ions to flow out of the cell. This action helps to stabilize the cell's electrical activity and can lead to muscle relaxation, vasodilation, and other physiological effects. They are used in various medical treatments, including managing hypertension and certain types of hair loss, such as androgenetic alopecia, by promoting blood flow and nutrient delivery to hair follicles.

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      Potassium Channel Therapeutics at the Bedside

      research Potassium Channel Therapeutics at the Bedside

      119 citations, June 2005 in “Journal of Molecular and Cellular Cardiology”
      Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
      K ATP Channels and Cardiovascular Disease

      research K ATP Channels and Cardiovascular Disease

      144 citations, March 2013 in “Circulation Research”
      K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
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