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Neonatal Allopregnanolone or Finasteride Administration Modifies Hippocampal K+ Cl− Co-Transporter Expression During Early Development in Male Rats

research Neonatal Allopregnanolone or Finasteride Administration Modifies Hippocampal K+ Cl− Co-Transporter Expression During Early Development in Male Rats

10 citations , May 2014 in “The Journal of Steroid Biochemistry and Molecular Biology”

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABA-A Receptors

248 citations , December 2011 in “Journal of Neuroscience”

Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.

research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability

January 2018

Early NAS level changes affect alcohol consumption vulnerability.

research Pathophysiological Mechanisms Implicated in Postpartum Depression

142 citations , January 2019 in “Frontiers in Neuroendocrinology”

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies

40 citations , December 2012 in “Epilepsia”

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

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