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research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABA_AReceptors

248 citations , December 2011 in “Journal of Neuroscience”

This study demonstrated that stress-derived neurosteroid THDOC shifts from inhibiting to activating the HPA axis under stress, presenting potential therapeutic targets for stress-related disorders.

Neonatal Allopregnanolone or Finasteride Administration Modifies Hippocampal K+ Cl− Co-Transporter Expression During Early Development in Male Rats

research Neonatal allopregnanolone or finasteride administration modifies hippocampal K+ Cl− co-transporter expression during early development in male rats

10 citations , May 2014 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that altering neurosteroid levels during early development in male rats can influence KCC2 levels, underscoring the role of neurosteroids in hippocampal maturation.

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