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research Isolation, Structural Elucidation, and Therapeutic Potentials of Root of Cucurbita Pepo

January 2021

Pumpkin roots contain compounds like Alpha-spinasterol, squalene, and palmitic acid, which may have health benefits like reducing depression, treating certain cancers, and having antibacterial properties.

research Erlotinib-Induced Skin Inflammation Is IL-1 Mediated in KC-Tie2 Mice and Human Skin Organ Culture

15 citations , October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.

research Monilethrix in Three Generations

6 citations , January 2008 in “Indian Journal of Dermatology”

Monilethrix, a genetic hair disorder causing fragile hair, affects three generations in a family.

research Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia

78 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

research Potassium Channel Openers: Pharmacological and Clinical Aspects

119 citations , October 1992 in “Fundamental & Clinical Pharmacology”

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

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community microneedle, any long term users damage?

in Microneedling 35 upvotes 1 year ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community Can you mix different topicals into 1 solution?

in Chat 2 upvotes 1 year ago

Combining minoxidil, pyrilutamide, and copper peptide is questioned, with advice to apply them separately to avoid reactions. Finasteride and minoxidil are recommended for effectiveness.

community Anyone know by what percentage Pyrilutamide or Ru decrease your androgens?

in Chat 1 upvotes 1 year ago

Pyrilutamide and RU58841 are androgen receptor antagonists that block receptors without significantly reducing testosterone or DHT levels. Any indirect effect on androgen levels is likely negligible.

community Hives/Rash from Kx 826 Pyrilutamide???

in Chat 1 upvotes 1 year ago

OP developed hives after using Kx 826 (Pyrilutamide) 1% twice daily for 3 weeks. The hives appeared on the arms, chest, and groin area.

community Anyone on Pyrilutamide 1%? What do you think of it?

in Chat 3 upvotes 1 year ago

Pyrilutamide 1% is being used for hair loss, with some users experiencing shedding but no regrowth yet. It may be too early to see results.

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