48 citations
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February 2010 in “Molecular biology reports” KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.
3 citations
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August 2018 in “Journal of Structural Biology” KAP8.1 protein is crucial for hair structure and interacts with keratin 85.
January 2014 in “China Animal Husbandry & Veterinary Medicine” The KAP8-1 gene affects skin, hair follicle development, and wool quality in different sheep varieties.
25 citations
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September 2014 in “SpringerPlus” Sheep have a unique gene, KAP8-2, that humans don't have, which may affect wool properties.
12 citations
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August 2011 in “Asian-Australasian Journal of Animal Sciences” This study investigated the polymorphisms of the keratin-associated protein 8.1 (KAP8.1) gene and its impact on fibre traits in 540 Inner Mongolian Cashmere goats. Six genotypes (AA, BB, CC, AB, AC, and BC) were identified, coded by three alleles (A, B, and C), with two SNPs (T113G and G116C) confirmed. Significant associations were found between genotypes and cashmere weight, cashmere length, and hair length, but not with fibre diameter. Genotypes AB and BB were linked to higher cashmere weight compared to AA. The study suggested that KAP8.1 gene polymorphisms, particularly a mutation at the 113 locus, could serve as a molecular marker for cashmere weight in these goats.