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research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis

31 citations , April 2016 in “Nature communications”

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

research Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial-Mesenchymal Interactions

92 citations , April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology”

Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.

Fabrication and Characterization of Dissolving Microneedles Containing Oryza Sativa L. Extract Complex for Enhancement of Transfollicular Delivery

research Fabrication and Characterization of Dissolving Microneedles Containing Oryza Sativa L. Extract Complex for Enhancement of Transfollicular Delivery

1 citations , August 2024 in “Polymers”

The P25H5-O microneedles effectively deliver substances through hair follicles and are safe for skin cells.

research Ontogeny and regional variability of keratin 2e (K2e) in developing human fetal skin: a unique spatial and temporal pattern of keratin expression in development

19 citations , April 1999 in “British Journal of Dermatology”

Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.

research The Human Type II Keratin Gene Cluster on Chromosome 12q13.13: Final Count or Hidden Secrets?

9 citations , February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

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Community Join

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community Three months on Finasteride

in Progress 6 upvotes 5 years ago

A user noticed rapid hair thinning and started using finasteride in October 2019. They also use Nizoral and Head & Shoulders with zinc pyrithione, hoping for regrowth and to delay baldness.

community PP405 will be available on Everychem soon apparently

in Research/Science 98 upvotes 4 months ago

PP405 is a potential hair loss treatment, but its safety and effectiveness are uncertain. Users advise caution and suggest waiting for more data before purchasing unverified versions.

community When you up the dose on oral Minoxidil

in Satire 3 years ago

This conversation is a satirical post about using increased doses of oral Minoxidil as a treatment for hair loss, which elicited some humorous responses. Additionally, Finasteride was mentioned in one response as an alternative treatment option.

community Started minoxidil in February 2025, this is September 2024–>July 2025

in Progress Pictures 160 upvotes 3 months ago

The user started oral minoxidil in February 2025 and noticed hair improvement, but paused due to pregnancy. They experienced minimal shedding and some facial hair growth as a side effect.

community I’ve been on Finasteride for 6.5 months. (5 months on 0.2mg and 1.5 months on 0.5mg) Here are the progress pictures.

in Progress Pictures 183 upvotes 7 months ago

A 21-year-old has been using finasteride for 6.5 months, starting with 0.25 mg daily and increasing to 0.5 mg, experiencing improved hair quality and no significant side effects. They have not used minoxidil due to convenience and health reasons, and they noticed progress in hair growth, particularly at the crown, after about 4 months.

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