research K6/ODC Transgenic Mice as a Sensitive Model for Carcinogen Identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
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5 / 284 resultsresearch Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODC Transgenic Mice
Dimethylarsinic acid speeds up skin tumor growth in certain mice.
research Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 In Vivo
High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.
research Keratin-6 Driven ODC Expression in Hair Follicle Keratinocytes Enhances Stemness and Tumorigenesis by Negatively Regulating Notch
ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
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