January 2013 in “Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine” This study found that YiFa compound medicated serum significantly promoted the proliferation of follicle stem cells and increased mRNA expression of K19 and β1 integrin in a mouse model, suggesting a potential mechanism for treating alopecia.
January 2013 in “Shiyong yixue zazhi” In this study with mouse follicle stem cells, astraglus polysaccharide increased markers of cell proliferation and gene expression, suggesting a potential mechanism for treating alopecia and promoting hair growth.
8 citations
,
April 2014 in “Clinical and Experimental Dermatology” This study suggests that eruptive vellus hair cysts often have atypical pathological changes and likely originate from the infrainfundibulum and sebaceous duct based on keratin expression analysis.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.
119 citations
,
September 2000 in “Journal of Biological Chemistry” This study found that the K19 promoter is active in certain gastrointestinal cancer cells and its activity is influenced by the interaction between GKLF and Sp1 transcription factors.