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research Environmental Pathobiology of Frontal Fibrosing Alopecia: Does Linalool Promote FFA Development and Progression?

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Linalool in personal care products may contribute to hair loss by damaging hair follicle stem cells and triggering harmful immune responses.

research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions

61 citations, July 2011 in “PLOS ONE”

Spermidine may help reduce hair loss and deserves further testing as a treatment.

research Environmental Pathobiology of Frontal Fibrosing Alopecia: Does Linalool Promote FFA Development and Progression by Inducing Epithelial Hair Follicle Stem Cell Damage and MICA Expression in the Bulge?

September 2022

Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.

research TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles

7 citations, January 2016 in “Laboratory Investigation”

TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.

research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling

35 citations, June 2012 in “PloS one”

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.