research Interventions for morphea
This review found that oral methotrexate plus oral prednisone may improve disease activity or damage in juvenile active morphea compared to placebo plus prednisone, but adverse events may slightly increase.
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5 / 1000+ resultsresearch Clinical Profile of Methotrexate-resistant Juvenile Localised Scleroderma
In this study, methotrexate effectively treated juvenile localized scleroderma in most cases, with few patients showing resistance and no identifiable profile for these resistant individuals.
research Bilateral morphea en coup de sabre: a rare presentationof linear morphea
This case report describes a young man with bilateral morphea en coup de sabre, which recurred after being quiescent, highlighting its association with previous head trauma and alopecia.
research Connective Tissue Disorders
This article reviews the spectrum of connective tissue disorders and discusses the role of autoantibodies, particularly in lupus erythematosus, but reports no new findings.
research Morphea: progress to date and the road ahead
This study highlights the need for further research on dysregulated immune and fibrotic pathways in morphea to better understand its pathogenesis and develop new biomarkers and therapies.
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1 / 94 resultscommunity Genetics are so weird and unpredictable
The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.
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