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Research

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research Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

701 citations , August 2014 in “Nature medicine”

This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.

research JAK inhibitors in dermatology: The promise of a new drug class

355 citations , January 2017 in “Journal of the American Academy of Dermatology”

This review reports no new results and highlights existing research suggesting JAK inhibitors may be effective in treating inflammatory skin conditions like alopecia areata, atopic dermatitis, psoriasis, and vitiligo.

research Emerging Topical and Systemic JAK Inhibitors in Dermatology

277 citations , December 2019 in “Frontiers in Immunology”

This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.

research JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis

223 citations , September 2018 in “Rheumatology”

This review examines clinical data on the efficacy and safety of JAK inhibitors used for immune-mediated conditions beyond rheumatoid arthritis, highlighting their potential therapeutic roles in various inflammatory diseases.

research Pharmacologic inhibition of JAK-STAT signaling promotes hair growth

159 citations , October 2015 in “Science Advances”

This study observed that applying JAK-STAT pathway inhibitors to mouse and human skin led to rapid hair growth by inducing the anagen phase of hair follicles.

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Learn

6 / 800 results

learn Hair Transplant

What is the DHI hair transplant technique? DHI harvests grafts like FUE and implants them with a pen-like tool that makes each small incision and places the graft in one step.
How should I care for my hair after a hair transplant? Follow your doctor's aftercare instructions, avoid sun exposure, and use gentle shampoo.

learn Scalp Micropigmentation

How often should I shave my head after scalp micropigmentation? For the shaved-head look, providers suggest shaving every 1-5 days. Density SMP worn under longer hair does not need this.
What should I avoid after scalp micropigmentation? Avoid sun exposure, swimming, sweating, and hair products after scalp micropigmentation.
What should I do before my scalp micropigmentation appointment? Providers often ask clients to skip alcohol and caffeine for 24-48 hours before SMP. Never stop a prescribed blood thinner, or aspirin a doctor told you to take, without asking that doctor.

learn Baricitinib

JAK inhibitor pill used for severe alopecia areata

learn Tofacitinib

JAK inhibitor pill, an immune-system drug

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

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Community Join

5 / 46 results

community No idea what's causing my hair thinning

in Chat 2 upvotes 1 year ago

The user is experiencing diffuse hair thinning despite using finasteride and oral minoxidil, with no hairline recession or bald spots. Suggestions include checking for telogen effluvium, considering a JAK inhibitor for potential autoimmune issues, and conducting further tests to rule out other causes.

community can someone help me identify these pls

in Treatment 10 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Seriously, why is this man such an angel 😭

in Satire 376 upvotes 1 year ago

Dr. Gary Linkov, a YouTuber and doctor, is praised for his free hair loss advice despite his own struggles with hair loss. Some users discuss the high cost of his consultations and treatments like oral minoxidil and Jak inhibitors.

community DUPA - 20 YO - Non responder to everything

in Finasteride/Dutasteride 13 upvotes 2 years ago

A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.

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Clinics

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All 12 clinic results →