This article reviews the structure and regulation of the ITGB6gene and discusses its role in integrin αvβ6 expression, with no new experimental results reported.
19 citations
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December 2015 in “European Journal of Human Genetics”
This study found that a novel rare variant in ITGB6 may cause intellectual disability, alopecia, and dentogingival anomalies in a specific Pakistani family, highlighting a potential role for ITGB6 beyond enamel formation.
99 citations
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January 2014 in “Nature communications”
In this study, researchers developed a method to differentiate human iPSCs into cells that can generate all lineages of hair follicles, potentially aiding treatments for hair loss and skin disorders.
This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.