research The ITGB6 gene: its role in experimental and clinical biology
This article reviews the structure and regulation of the ITGB6 gene and discusses its role in integrin αvβ6 expression, with no new experimental results reported.
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research Expansion of the spectrum of ITGB6-related disorders to adolescent alopecia, dentogingival abnormalities and intellectual disability
This study found that a novel rare variant in ITGB6 may cause intellectual disability, alopecia, and dentogingival anomalies in a specific Pakistani family, highlighting a potential role for ITGB6 beyond enamel formation.
research 464 Spatial transcriptomics links gene expression profiles to functional and structural traits of darkly pigmented skin
Dark skin has stronger barriers and structure due to specific gene activity.
research Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics
This study identified several DPC-specific proteins, including ITGB1, IGFBP3, and THBS1, as potential biomarkers for hair growth modulation through proteomic and network analysis.
research ROCK inhibitor Y-27632 maintains the propagation and characteristics of hair follicle stem cells.
This study found that the ROCK inhibitor Y-27632 maintains self-renewal and stemness of hair follicle stem cells in vitro, supporting their potential for tissue engineering applications.
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