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GlossaryCD49f (ITGA6)

protein aiding cell adhesion and migration, crucial for tissue maintenance

CD49f, also known as Integrin alpha-6 or ITGA6, is a protein found on the surface of certain cells that helps them stick to their surroundings. It plays a crucial role in cell adhesion, migration, and signaling, which are important for processes like wound healing and the maintenance of tissues, including hair follicles.

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research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human-Induced Pluripotent Stem Cells

10 citations , August 2020 in “Current protocols in stem cell biology”

Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.

research Hair Follicle Specific ACVR1/ALK2 Critically Affects Skin Morphogenesis and Attenuates Wound Healing

10 citations , May 2017 in “Wound Repair and Regeneration”

Overexpression of ALK2 in hair follicles disrupts skin development and slows wound healing.

research Discovery and Functional Analysis of Secondary Hair Follicle miRNAs During Annual Cashmere Growth

3 citations , January 2023 in “International journal of molecular sciences”

Certain miRNAs play a key role in the growth of cashmere by affecting hair follicle development and regeneration.

research High Migratory Activity of Dermal Sheath Cup Cells and Clinical Efficacy in Autologous Therapy for Hair Loss

November 2023 in “Journal of Dermatological Science”

Cells that move well may improve hair loss treatments by entering hair follicles.

research Whole-Genome SNP Genotyping Mapped a Novel Locus for Hereditary Hypotrichosis on Chromosome 2q31.1–q32.2

May 2015 in “Journal of Dermatological Science”

Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.

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community Cure/better treatment options in the future

in Chat 11 upvotes 1 year ago

The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.