research Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.
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research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
This study found that sebaceous glands predominantly exhibit oxidative activity of the type 2 17β-hydroxysteroid dehydrogenase isozyme, which is not inhibited by 13-cis retinoic acid.
research Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human
This study found significant species differences in the enzyme activity and inhibitor affinities of prostatic 5α-reductases from rats, dogs, and humans, with variable potencies for different 3-oxo-4-azasteroid inhibitors across species.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
This review discusses how sex hormone levels and local steroid synthesis influence gender differences in aging skin, reporting no new clinical results.
research Differences in reproductive toxicology between alopecia drugs: an analysis on adverse events among female and male cases
This study found that finasteride was associated with more reproductive adverse effects, including sexual dysfunction in men and fetal harm in women, compared to minoxidil in reported alopecia cases.
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1 / 1000+ resultscommunity Is this finasteride brand legit?
The conversation discusses the use of dutasteride and minoxidil for hair loss treatment, with concerns about potential side effects and the effectiveness of dutasteride compared to finasteride. The user is advised to monitor for side effects and consult with a doctor, while also considering the differences between the medications.
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