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research Immunohistochemical detection of cytochrome P450 isoenzymes in cultured human epidermal cells.

19 citations , December 1990 in “Journal of Histochemistry & Cytochemistry”

This study found that cultured human foreskin cells and a human keratinocyte cell line continue to express specific cytochrome P450 isoenzymes, unlike keratinocytes derived from hair follicles.

research Enzyme Typing of Human Hair Roots

27 citations , April 1978 in “Journal of Forensic Sciences”

This study explored the potential of using isoenzyme detection after electrophoresis to characterize human hair, though no new clinical results are reported.

research Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles

35 citations , July 2010 in “The FEBS journal”

In this study, researchers identified a highly reactive, isozyme-specific sequence for TGase 3, contributing to understanding its distinct functional role and activity distribution in the mouse epidermis.

research Analytical methods of dutasteride: An overview

December 2023 in “Annals of phytomedicine”

This study reports that dutasteride, used alone or with tamsulosin, effectively reduces acute urine retention and surgery risk in men with benign prostatic hyperplasia, and may lower prostate cancer incidence, suggesting potential chemopreventive benefits.

research A concise review- Development of an analytical method and validation of dutasteride

January 2025 in “Current Trends in Pharmacy and Pharmaceutical Chemistry”

This review examines recent advancements in analytical techniques used to quantify dutasteride, a medication for enlarged prostate, in various biological samples and its commercial forms, emphasizing methods such as HPTLC, GC-MS, and HPLC.

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community Green tea/ soy Isoflavones supplements for MPB

4 upvotes 5 years ago

Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.

community So many horror stories about switching from fin to dut

in Finasteride/Dutasteride 58 upvotes 7 months ago

Switching from finasteride to dutasteride can cause initial shedding, but many see long-term hair regrowth and stabilization. Responses vary, with some experiencing fewer side effects and others finding it less effective.

community Creatine is the opposite of minoxidil !

324 upvotes 11 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Results from 272 diode Red Light Therapy hat exclusively.

254 upvotes 7 months ago

A user reported noticeable hair regrowth using a 272 diode red light therapy hat over 11 months without Minoxidil or Finasteride. Opinions vary on its effectiveness compared to traditional treatments, with some suggesting combining therapies for better results.

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