research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
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5 / 1000+ results research VEGF165 Induces Differentiation of Hair Follicle Stem Cells Into Endothelial Cells and Plays a Role in In Vivo Angiogenesis
The study investigated the role of VEGF165 in inducing the differentiation of hair follicle stem cells (HFSCs) into vascular endothelial cells, highlighting its potential in angiogenesis. It was found that VEGF165, a key factor in angiogenesis, could effectively induce HFSCs to differentiate into endothelial cells, with the Notch signaling pathway potentially influencing this differentiation process. Additionally, in vivo experiments demonstrated that HFSCs could enhance angiogenesis by promoting host-derived neovascularization. These findings suggested that HFSCs might serve as a promising cell source for vascular tissue engineering and cell transplantation, particularly in treating ischemic diseases.
research Diseases That Affect the Pinna
The document describes skin diseases affecting the outer ear in dogs and cats, their spread to other body parts, and treatment options.
research An Update on the Roles of the Complement System in Autoimmune Diseases and the Therapeutic Possibilities of Anti-Complement Agents
Anti-complement agents could effectively treat autoimmune diseases with fewer side effects.
research Exosomal MicroRNA-Based Therapies for Skin Diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
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5 / 8 resultscommunity Ru58841 ruined my life. Here’s why.
User experienced shortness of breath, high blood pressure, red eyes, and eye floaters after using RU58841 for hair loss. They warn others to avoid RU58841 and stick to finasteride, minoxidil, and dutasteride.
community Quit vaping/smoking = 80% less loss
Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.
community Atherosclerosis as cause of balding and treatment
Hair loss may be caused by calcification of capillaries in the scalp, restricting blood flow to hair follicles. A daily treatment regimen including high doses of Vitamins D and K, Magnesium, and Nattokinase could potentially decalcify these capillaries, improving blood flow and hair growth. However, some users warn against excessive Vitamin D intake and emphasize the need for medical consultation.
community "Minoxidil and Caffeine: Reason behind hyper responders and non-responders."
Minoxidil and caffeine may interact, affecting hair growth results. Users shared mixed experiences, with some noticing improvements without caffeine and others still seeing results despite coffee consumption.
community Pyrilutamide Phase 3 on its way
Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.