research Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders
This review highlights the critical role of iron in skin functions and suggests potential dermatologic therapies targeting the iron-skin axis.
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research Androgenetic alopecia: may growth factor mimetic oligopeptides supplement minoxidil and finasteride therapy?
In this case report, a 35-year-old man with androgenetic alopecia showed significant improvement in hair thickness and density after six months of conservative therapy with topical minoxidil, oral finasteride, and a gel with oligopeptides, caffeine, and taurine.
research Deferasirox, an oral iron chelator, prevents hepatocarcinogenesis and adverse effects of sorafenib
In this study, combining deferasirox with sorafenib significantly reduced liver fibrosis and preneoplastic lesions in rats while also lessening adverse effects compared to sorafenib alone.
research Genetic analysis of a novel antioxidant multi-target iron chelator, M30 protecting against chemotherapy-induced alopecia in mice
This study found that M30 may protect against cyclophosphamide-induced alopecia in mice by enhancing hair growth and preventing abnormal hair, suggesting its potential as a treatment.
research Iron Chelators in the Management of Autoimmune-Induced Alopecia: A Focus on Hypoxia-Inducible Factor 1 Modulation and Hair Restoration
This study highlighted the potential of iron chelators, deferoxamine and deferiprone, to improve hair density, thickness, and elasticity and reduce hair loss by up to 66.8% over six months in individuals with autoimmune alopecia, suggesting they may offer a promising therapeutic option.
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