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GlossaryCXCL10 (IP-10)

signaling protein that attracts immune cells to inflammation sites

CXCL10, also known as Interferon gamma-induced protein 10 (IP-10), is a type of signaling protein called a chemokine. It plays a crucial role in the immune system by attracting white blood cells to sites of inflammation or infection. This protein is particularly important in conditions where the immune response needs to be regulated, such as autoimmune diseases and certain types of hair loss like alopecia areata.

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research Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin, and MIP-1α in the Adipose-Derived Stem Cell Secretome in Androgenetic Alopecia

1 citations, February 2022 in “Experimental Dermatology”

Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.

research Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin and MIP-1α in Adipose Derived Stem Cells Secretome in Androgenetic Alopecia

January 2021

Higher levels of certain proteins in hair loss areas may help understand and treat hair loss.

research Purification and Characterization of an Immuno-Stimulatory Compound from the Water Extract of Royoporus Badius (Pers.) A.B. De.

January 2018

A new compound from Royoporus badius activates immune cells and induces inflammatory responses.

research What Is Behind the 'Swarm of Bees' in Alopecia Areata

7 citations, November 2018 in “British Journal of Dermatology”

Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.

research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata

64 citations, July 2016 in “Journal of Immunology”

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

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community Phase II Clinical Trial for TDM-105795 started recruiting

in Research/Science 23 upvotes 1 year ago

A Phase II clinical trial for TDM-105795 has started recruiting in the US, and it might be a promising treatment for hair loss. Many hair loss drugs, including this one, originate from China.

community Phase II for Technoderma Therepeutic's TDM-105795 set to begin in April tentatively

in Research/Science 41 upvotes 1 year ago

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

community HairClone aiming to 'Make Hairloss History' Launches Crowdfunding Campaign

29 upvotes 5 years ago

The post and conversation are about skepticism towards HairClone's crowdfunding campaign for a hair loss cure, with users expressing doubt and calling it a scam. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Increasing activity of the sult1a1 enzyme via alkalizing agent and tretinoin for better response to topical minoxidil

in Research/Science 4 upvotes 3 months ago

Increasing the sult1a1 enzyme on the scalp may improve response to topical minoxidil. The user suggests using a baking soda solution, DMSO, and tretinoin to enhance enzyme activity and minoxidil effectiveness.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 5 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

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