17 citations
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August 1967 in “JAMA” The rapid corticotropin test is a quick and simple way to diagnose adrenal insufficiency.
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March 1976 in “Journal of Investigative Dermatology” 87 citations
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June 2010 in “Stem Cell Research & Therapy” 11 citations
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September 2010 in “PubMed” The study developed a rapid LC-MS/MS method to determine dihydroartemisinin (DHA) in rat plasma and tissues, comparing the pharmacokinetics and tissue distribution of DHA in nanostructured lipid carriers (DHA-NLC) versus a DHA solution. The DHA-NLC exhibited a longer mean residence time and higher AUC values in the liver, spleen, lung, brain, and muscle, but lower in the heart and kidney compared to the DHA solution. This indicated that DHA-NLC could be a promising sustained-release and drug-targeting system for antitumor drugs, potentially allowing for reduced dosage and decreased systemic toxicity.
2 citations
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January 1994 in “Yakubutsu dōtai” Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.