16 citations
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January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
77 citations
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August 1986 in “Archives of Dermatology” This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.
11 citations
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August 1986 in “Archives of Dermatology” This case report describes a patient with skin and nail hyperpigmentation and premature gray hair due to vitamin B12 deficiency, which were reversed after treatment with cyanocobalamin.
June 2021 in “Asian Journal of Medical Sciences” This case study highlights that vitamin B12 deficiency can cause reversible hyperpigmentation, illustrated by a vegetarian female patient whose skin lesions improved after treatment.
1 citations
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January 2013 in “Surgical Science” This study observed that vitamin and iron deficiencies were similarly prevalent in the first post-surgical year for patients undergoing sleeve gastrectomy and Roux-en-Y gastric bypass, except for more frequent vitamin B6 deficiency in sleeve gastrectomy patients.