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Glossary Intralesional Injections

directly injecting medication into a specific skin lesion

Intralesional Injections, also known as Intralesional Therapy, involve directly injecting medication into a specific lesion or affected area of the skin. This targeted approach is often used to treat conditions like alopecia areata, psoriasis, and keloids, allowing for high concentrations of the drug at the site of the problem while minimizing systemic side effects.

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research Benefit of different concentrations of intralesional triamcinolone acetonide in alopecia areata: An intrasubject pilot study

50 citations , July 2015 in “Journal of the American Academy of Dermatology”

This study found that 2.5 mg/mL triamcinolone acetonide injections were as effective as higher doses for treating limited, patchy alopecia areata, while minimizing side effects like skin atrophy.

research The place of intralesional steroid therapy in dermatology

39 citations , March 1976 in “British Journal of Dermatology”

This article reviews the use of intralesional steroid therapy in dermatology, highlighting its application in conditions like nail disorders and cystic acne, but it reports no new clinical results.

research Dermoscopic evaluation of therapeutic response to an intralesional corticosteroid in the treatment of alopecia areata

35 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.

research Clinical Evaluation of Intralesional Triamcinolone

2 citations , March 1964 in “Archives of Dermatology”

This study found no significant difference in the therapeutic response to intralesional triamcinolone acetonide at concentrations of 2.5, 5, and 10 mg/mL for various dermatologic conditions.

research 016 Anesthetics Prior to Keloid Injections: A Painless Approach

October 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

This study suggests that PGD2 may increase testosterone production in keratinocytes through oxidative stress pathways, with n-acetyl-cysteine blocking this effect.

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community 1mg of finasteride/2 sessions of Kenalog injections/ Clobetasol (4 months into treatment)

5 upvotes 2 months ago

The user is undergoing treatment for hair loss using finasteride, Kenalog injections, and Clobetasol, along with vitamin D and collagen supplements. They are considering additional treatments like minoxidil and microneedling, and there is discussion about whether the hair loss is due to stress, alopecia areata, or a scarring condition like lichen planopilaris.

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