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GlossaryIntralesional Injections (Intralesional Therapy)

directly injecting medication into a specific skin lesion

Intralesional Injections, also known as Intralesional Therapy, involve directly injecting medication into a specific lesion or affected area of the skin. This targeted approach is often used to treat conditions like alopecia areata, psoriasis, and keloids, allowing for high concentrations of the drug at the site of the problem while minimizing systemic side effects.

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research Transient Chemotherapy-Induced Alopecia After Intralesional 5-Fluorouracil Treatment of Keloids

3 citations, August 2019 in “JAAD Case Reports”

Temporary hair loss can occur after 5-fluorouracil treatment for keloids.

research Genetic Transformation of Keratoacanthoma-Type Cutaneous Squamous Cell Carcinoma Following Intralesional Chemotherapy

2 citations, April 2018 in “Journal of Investigative Dermatology”

Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

research Malignant Epithelial Tumors: Part II. Therapy and Prevention

5 citations, January 2013 in “Journal der Deutschen Dermatologischen Gesellschaft”

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

research Mutational Landscape of Extramammary Paget Disease

April 2018 in “Journal of Investigative Dermatology”

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

research Post Acne Scarring: A Review

81 citations, January 2003 in “Journal of cosmetic and laser therapy”

New techniques have improved acne scar treatment, but multiple tailored sessions are often needed.

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community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 62 upvotes 4 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.