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Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction

research Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction

20 citations, June 2017 in “Hormone Molecular Biology and Clinical Investigation”

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men

31 citations, January 2017 in “Advances in Experimental Medicine and Biology”

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

research Compendium of Polycystic Ovarian Syndrome and Its Relevance in Glycation and Diabetes

1 citations, January 2022 in “Journal of experimental and clinical medicine”

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues

4 citations, November 2022 in “Frontiers in Immunology”

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm

17 citations, January 2020 in “The World Journal of Men's Health”

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

View more "intrahepatic lipid accumulation" in research →

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community Anyone experienced weight gain on dutasteride?

in Finasteride/Dutasteride 6 upvotes 2 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 2 months ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community Efficacy of different dutasteride doses vs finasteride

in Research/Science 123 upvotes 1 year ago

Dutasteride doses matter for hair loss treatment and are more effective than finasteride. RU58841 is suggested for better gains, but side effect profiles should be considered.

community How much would a high dose dutasteride scalp dht inhibition be?

in Finasteride/Dutasteride 10 upvotes 8 months ago

The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.