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Frontline, gold standard treatment for combatting androgenic alopecia
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3 / 3 resultslearn Epidermal Growth Factor
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
Research
5 / 1000+ resultsresearch Intracellular Protons Accelerate Aging and Activate Aging Hallmarks in Mice
Acid inside cells speeds up aging and turns on aging signs in mice.
research Mechanisms of Proton Inhibition and Sensitization of the Cation Channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Activation of Temperature-Sensitive Ca2+-Permeable TRPV3 Channels by Natural α-Hydroxyl Acids Causes Exfoliation for Skin-Resurfacing
Natural α-hydroxyl acids cause skin exfoliation by activating TRPV3 channels.
research The Optimal Holding Solution and Temperature for Hair Follicle Grafts
Best solution for storing hair grafts is saline with ATP at 4 degrees Celsius, but no definitive best method was confirmed.
research Potassium Channel Therapeutics at the Bedside
Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.
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5 / 20 resultscommunity Minoxidil and Caffeine - opposite effects yet comboed together?
Minoxidil and caffeine are discussed for hair loss treatment. The user questions the logic of combining them due to their opposing effects on adenosine receptors.
community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)
Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.
community GT20029 and PP405 the new fin and min that we been waiting for ?
PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.
community Meta analysis of minoxidil only vs 5AR inhibitors
Oral dutasteride is the most effective for hair regrowth, followed by oral finasteride and minoxidil. Topical finasteride combined with minoxidil is recommended for those avoiding systemic DHT reduction.
community How does hair loss and recovery work?
Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.