research Intracellular protons accelerate aging and switch on aging hallmarks in mice
This study found that sustained intracellular acidosis in mice was associated with shortened lifespan, early aging signs, and impaired autophagy.
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5 / 1000+ resultsresearch Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
This study found that acid regulation of the TRPV3 channel can inhibit its function from outside the cell while facilitating it from inside, providing insights into skin barrier and disorder mechanisms related to tissue acidosis.
research Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
This review discusses the multifaceted actions of metformin in polycystic ovary syndrome and reports no new clinical results; the authors emphasize metformin's potential benefits in both cardiometabolic and reproductive aspects of PCOS.
research In search of decoding the syntax of the bioelements in human hair – A critical overview
This review presents the practice of using hair bioelement analysis to assess nutritional status or environmental exposure, proposing complex interactions and hypotheses regarding depression and autism but reports no new clinical results.
research The optimal holding solution and temperature for hair follicle grafts
This article discusses various holding solutions for hair transplant grafts and reports no new research findings; the authors emphasize the need for comparative studies.
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