31 citations
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February 1983 in “American Journal of Clinical Nutrition” In this study, two patients with long-term total parenteral nutrition and no biotin intake experienced hair regrowth after biotin supplementation, suggesting biotin deficiency can lead to alopecia.
5 citations
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January 2024 in “American Journal of Translational Research” This research highlighted that the gut microbiota may influence ovarian health, suggesting it could be used as a biomarker for early diagnosis and treatment of diseases like PCOS, ovarian insufficiency, and ovarian cancer due to its impact on hormone levels.
September 2025 in “International Journal of Molecular Sciences” This study found that Hashimoto's thyroiditis and alopecia areata show distinct gut microbial patterns, with specific microbes like Bacteroides fragilis and Microbacterium sp. T32 potentially linked to autoimmune activity.
February 2026 in “Animals” In this study, supplementing low-protein diets with 0.75% methionine maintained growth performance, improved fur quality, enhanced nutrient utilization, and supported intestinal microbiota balance in blue foxes, with significant results on several biochemical parameters and nutrient digestibility observed.
82 citations
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August 2017 in “Cell Reports” This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.