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research Intermediate hair follicles: a new more clinically relevant model for hair growth investigations

30 citations , May 2010 in “British Journal of Dermatology”

This study found that intermediate hair follicles are morphologically distinct from terminal follicles and offer a novel model for developing new alopecia therapies despite being technically more challenging to study.

research Single-Cell Transcriptomic Identification of a Proliferative Intermediate State During Early Anagen Hair Follicle Regeneration

August 2026 in “Genes”

This study identified a proliferative intermediate transcriptional state associated with the transition from secondary hair germ cells to lower hair follicle-associated cells during early hair follicle regeneration in mice.

Prostaglandin F2α Stimulates Growth of Human Intermediate Hair Follicles in Ex Vivo Organ Culture with Potential Clinical Relevance

research Prostaglandin F2α stimulates the growth of human intermediate hair follicles in ex vivo organ culture with potential clinical relevance

June 2025 in “Frontiers in Physiology”

This study demonstrated that PGF 2α significantly stimulates hair growth in human hair follicles via a receptor-driven mechanism, with a notably stronger response in intermediate follicles than in terminal ones, suggesting potential clinical significance for conditions like alopecia.

research The growth of human hair

September 1984 in “Journal of Biological Education”

Human hair growth involves active, resting, and intermediate phases, and examining plucked hairs can teach students about hair biology and diseases.

Nestin as a Marker of Unipotent Epithelial Progenitor Cells Differentiating into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles

research Nestin as a marker of unipotent epithelial progenitor cells differentiate into outer root sheath keratinocytes in embryonic and adult hair follicles

June 2022 in “Research Square (Research Square)”

This study revealed that nestin-expressing progenitor cells capable of becoming ORS keratinocytes are present during both hair follicle development and in adult hair follicles.

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community Another follow up. 2 years and 7 months on Fin and Min. For the first time in years, I can grow my hair.

1046 upvotes 10 months ago

The user experienced significant hair regrowth using oral finasteride (1 mg) for 2 years and 7 months and topical minoxidil (5%) for about 13 years, with no side effects reported. The user noted many shedding phases but observed stronger hair regrowth each time, leading to increased confidence and positive feedback from others.

community Chlorine dioxide: An effective product?

5 upvotes 1 year ago

Chlorine dioxide was discussed as a potential hair growth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.

community Guys using oral dut after multiple years of fin, how many gains did you have?

11 upvotes 3 months ago

Switching from finasteride to dutasteride did not result in significant hair regrowth for most users, with some experiencing worsening hair conditions or side effects. Many users continue using minoxidil alongside these treatments.

community 7 months in on Finasteride + Minoxodil... no results. Feeling bummed.

in Chat 4 upvotes 4 months ago

The user is feeling discouraged after seven months of using finasteride and minoxidil with no visible results for hair loss. Suggestions include continuing treatment for up to 12 months, considering microneedling, checking for deficiencies, and possibly trying dutasteride or oral minoxidil.

community 7 months using Dutasteride Horror, before and after

in Minoxidil 51 upvotes 11 months ago

The user experienced significant hair loss after starting dutasteride, despite improved libido and gym performance. They previously used finasteride but stopped due to side effects and are considering combining treatments or a hair transplant.

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