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research Single-Cell Transcriptomic Identification of a Proliferative Intermediate State During Early Anagen Hair Follicle Regeneration

August 2026 in “Genes”

This study identified a proliferative intermediate transcriptional state associated with the transition from secondary hair germ cells to lower hair follicle-associated cells during early hair follicle regeneration in mice.

research Single-cell sequencing reveals the intermediate cell state and function of dermal papilla cells in the hair follicle cycle of cashmere goats

May 2020 in “Research Square (Research Square)”

This study used cashmere goats to reveal distinct intermediate states of dermal papilla cells, each with specific roles in hair growth, shedding, and regeneration.

research Isolation and Characterization of a Novel Hair Follicle–Specific Gene, Hacl-1

25 citations , May 1994 in “Journal of Investigative Dermatology”

This study identified a novel gene, hacl-1, that is specifically expressed in the hair follicles of ICR mouse skin and is associated with their active state.

research Single-cell sequencing reveals the new existence form of dermal papilla cells in the hair follicle regeneration of cashmere goats

2 citations , February 2022 in “Genomics”

This study used cashmere goats to map the differentiation of dermal papilla stem cells and identified key intermediate cell states involved in hair follicle regeneration.

research Emerging roles of transit‐amplifying cells in tissue regeneration and cancer

32 citations , July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology”

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

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community Chlorine dioxide: An effective product?

5 upvotes 1 year ago

Chlorine dioxide was discussed as a potential hair growth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community 28m - Last 26 days have been great

15 upvotes 9 months ago

A 28-year-old male shares his hair regrowth progress using finasteride, topical and oral minoxidil, hair peptide serum, ketoconazole shampoo, dermastamping, multivitamins, and a high-protein diet. He reports noticeable hair growth and minor side effects, emphasizing patience as key to success.

community 1 year results on dut 0.5mg 24M. Big thanks to this community for helping me to fight norwood reaper

in Progress Pictures 63 upvotes 1 year ago

The user achieved significant hair regrowth using only dutasteride, noticing results after 8-9 months despite initial shedding. They did not use minoxidil due to inconvenience but still experienced permanent hair growth.

community 5 Month on Oral Min and Oral Fin

825 upvotes 1 month ago

The user experienced significant hair regrowth using 1.25mg finasteride, 5mg oral minoxidil, ketoconazole shampoo, and scalp massages, with the main side effect being excessive body hair growth. They are surprised by the results, as even doctors are shocked by the effectiveness, and they attribute their success to genetics.

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