learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research Demethylation of ITGAV Accelerates Osteogenic Differentiation in a Blast-Induced Heterotopic Ossification In Vitro Cell Culture Model 11 citations, December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research Mechanical Force Activation of TGF-β Signaling Controls Hair Follicle Regression April 2023 in “Journal of Investigative Dermatology” Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.
research The Role of Integrin AlphaVbeta6 in Impaired Wound Healing and Hair Follicle Regeneration January 2010 Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy 54 citations, January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
research Expansion of the Spectrum of ITGB6-Related Disorders to Adolescent Alopecia, Dentogingival Abnormalities, and Intellectual Disability 19 citations, December 2015 in “European Journal of Human Genetics” A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.