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research INSULIN-LOWERING MEDICATIONS IN POLYCYSTIC OVARY SYNDROME

39 citations , September 2000 in “Obstetrics and Gynecology Clinics of North America”

This article reviews evidence on hyperinsulinemia and insulin resistance in women with polycystic ovary syndrome and evaluates therapeutic responses to insulin-lowering agents, reporting no new clinical findings.

research Trans-Epidermal Elimination Due to Insulin Formulation: Report of a Rare Adverse Effect

July 2025 in “Indian Dermatology Online Journal”

In this case report, researchers documented a rare instance of trans-epidermal elimination of insulin formulation in a 45-year-old woman with diabetes, suggesting that insulin or its excipients may have caused a granulomatous reaction leading to skin lesions at injection sites and impaired diabetes control.

research SAT383 Case Study: Impact of Weight Reduction and Oral Contraceptive Pills on Hyperandrogenism

October 2023 in “Journal of the Endocrine Society”

In this case study, the authors observed that weight loss coupled with a brief use of oral contraceptives was associated with normalized testosterone levels in a woman with severe hyperandrogenism and PCOS.

research Interventional studies for polycystic ovarian syndrome in children and adolescents

12 citations , January 2010 in “Pediatric Health”

This review discusses treatment strategies for PCOS, focusing on using insulin-sensitizing medications alongside weight reduction and exercise to improve hyperinsulinemia and hyperandrogenism, and reports no new results.

research The skin and obesity

January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences”

This review article highlights that obesity is a significant risk factor for several inflammatory skin conditions, such as psoriasis and atopic eczema, contributing to increased overall morbidity among those affected.

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community Insulins impact on androgen levels

16 upvotes 4 years ago

Controlling insulin levels through intermittent fasting and a low glycemic diet may improve hair quality by reducing androgens. It's important to maintain proper nutrition, including electrolytes and protein, during fasting.

community What do you think about this? he says one of the causes of pattern hair loss is scars and it can be fixed

3 months ago

The conversation discusses hair loss treatments, focusing on insulin resistance, microneedling with topical melatonin, and stress reduction. Users express skepticism about the advice, preferring proven treatments like minoxidil and finasteride, while some mention alternative methods like dermal incisions and verteporfin for reducing fibrosis.

community The Association between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men

136 upvotes 1 year ago

Excessive sugar consumption may contribute to male pattern hair loss by increasing androgen sensitivity and insulin resistance, but genetics play a significant role. Treatments like minoxidil and finasteride are suggested for managing hair loss, while reducing sugar intake and maintaining a healthy lifestyle may help mitigate its progression.

community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

13 upvotes 4 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

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Learn

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learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn Vascular Endothelial Growth Factor

learn Epidermal Growth Factor

learn sh-Polypeptide-7

learn Metformin

Can metformin improve scalp health in people with insulin resistance or PCOS? There is no controlled trial showing that metformin improves scalp hair. The PCOS studies most often cited measured unwanted body hair, not scalp density, and a published case report describes hair loss during metformin treatment; any use for hair would be off-label and a decision for a prescribing doctor.

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Hair Systems
Shreeji Cosmodent Dental Implant & Laser Hair ReductionAhmedabad, Gujarat · IN

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