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research Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

8 citations , January 2019 in “Annals of Dermatology”

Among cultured sebocytes, this study found that bilobetin significantly inhibited lipid production induced by IGF-1, suggesting potential for use in acne treatment.

research Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1

37 citations , June 1996 in “Journal of cellular physiology”

This study found that IGF1, retinoic acid, and dexamethasone increase IGFBP-3 production in cultured human dermal papilla cells, potentially inhibiting IGF1 action on hair growth.

research Dietary isoflavone increases insulin-like growth factor-I production, thereby promoting hair growth in mice

29 citations , March 2011 in “The Journal of Nutritional Biochemistry”

Eating isoflavone can help mice grow hair by increasing a growth factor.

research Promotion of Insulin-Like Growth Factor-I Production by Sensory Neuron Stimulation; Molecular Mechanism(s) and Therapeutic Implications

23 citations , December 2008 in “Current medicinal chemistry”

This study reports that stimulating sensory neurons with capsaicin and isoflavone increases IGF-I production, promoting hair growth in mice and human volunteers with alopecia.

Effect of Topical Application of Raspberry Ketone on Dermal Production of Insulin-Like Growth Factor-I in Mice and on Hair Growth and Skin Elasticity in Humans

research Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans

39 citations , March 2008 in “Growth hormone & IGF research”

Raspberry ketone may help grow hair and improve skin elasticity.

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Community Join

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community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Purchasing and Shipping Alpecin DMG to the United States.

3 upvotes 11 months ago

A user is seeking help to purchase and ship Alpecin DMG to the United States due to issues with eBay sellers. They prefer Alpecin DMG over minoxidil because of concerns about minoxidil's effects on insulin production, as they have diabetes.

community Will PP405 be prohibitively expensive or will it be roughly the same as fin or min?

in Research/Science 8 upvotes 1 year ago

PP405 is expected to be more expensive than finasteride and minoxidil initially due to patent protection, but not as costly as life-saving medications like Ozempic. The price may decrease after the patent expires, but initially, it might be around $100 per month, making it potentially unaffordable for many.

community Severe copper deficiency, and also zinc deficiency. Looking for testimonials.

2 upvotes 9 months ago

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

community 22M High Estrogen after blood test

1 upvotes 7 months ago

A 22-year-old male with high estrogen levels is considering finasteride for hair loss but is concerned about potential side effects due to his hormone levels and family history of diabetes. Users suggest consulting a doctor, possibly an endocrinologist, and considering lifestyle changes like diet and exercise to address visceral fat and insulin resistance before starting treatment.

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Learn

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learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn sh-Polypeptide-7

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Epidermal Growth Factor

learn Inulin

learn Metformin

Can metformin improve scalp health in people with insulin resistance or PCOS? There is no controlled trial showing that metformin improves scalp hair. The PCOS studies most often cited measured unwanted body hair, not scalp density, and a published case report describes hair loss during metformin treatment; any use for hair would be off-label and a decision for a prescribing doctor.

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